We have used Trafalgar and Globus. Both do use good hotels. However, use the Internet to preview the hotels for location and quality. Trafalgar "Best of Germany" used excellent hotels but several were near the autobahn vs. inner city. Berlin and Munich were excellent locations and Hiltons. Globus "Italian Mosaic" hotels were OK, not outstanding. Venice was disappointing since it was located in Metz or out of the city. Same goes the Albani Hotel in Rome. The hotel in Florence was a dump, located near the train station. Globus did stay 2 nights for the most part, Trafalgar 1 night.
Much more bus time with Trafalgar, plus the "content" was not as good as Globus. With Globus there were more inside visits and local tour guides with wireless headphones, only one with Trafalgar. We will probably return to Globus for Spain and the Benelux countries--after I check out the hotels.